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In the released videos so far, we see a man combining the Omni with an Occulus Rift headset and running around gunning down enemies in Team Fortress 2. Another is seen strolling through Skyrim.
Certain in-game features would still require a controller, but throw in some Kinect support (which is already there) and we're starting to see some pretty impressive Virtual Reality gaming in the next year or so.
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source
The source link contains a video and it is cool as hell. Klick and watch it :-D.